Cart
sales@molnova.com
Ertugliflozin L-pyroglutamic acid
CAS No. 1210344-83-4
Ertugliflozin L-pyroglutamic acid( PF-04971729 L-pyroglutamic acid )
Catalog No. M26680 CAS No. 1210344-83-4
Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 50 | In Stock |
|
| 25MG | 74 | In Stock |
|
| 50MG | 87 | In Stock |
|
| 100MG | 129 | In Stock |
|
| 200MG | 188 | In Stock |
|
| 500MG | 322 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameErtugliflozin L-pyroglutamic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionErtugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM.
-
DescriptionErtugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.(In Vitro):Ertugliflozin L-pyroglutamic acid demonstrated >2000-fold selectivity for SGLT2 over SGLT.(In Vivo):The oral administration of Ertugliflozin L-pyroglutamic to rats acid showed concentration-dependent glucosuria.
-
In Vitro——
-
In Vivo——
-
SynonymsPF-04971729 L-pyroglutamic acid
-
PathwayOthers
-
TargetOther Targets
-
RecptorCaspase-3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1210344-83-4
-
Formula Weight566
-
Molecular FormulaC27H32ClNO10
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 125 mg/mL (220.85 mM)
-
SMILESOC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kravchenko DV, et al. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. J Med Chem. 2005 Jun 2;48(11):3680-3.
molnova catalog
related products
-
Neurokinin B TFA
Neurokinin B TFA belongs to the tachykinin family.Neurokinin B binds to a series of GPCR, including neurokinin receptors 1 (NK1R), NK2R, and nk3r, to modulate their biological effects
-
DYKDDDDK
DYKDDDDK
-
RR-11a analog
RR-11a analog is a potent and selective asparaginyl endopeptidases (AE) (Legumain) inhibitors(IC50 values of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively).
